Ann Worthington (née Pendelbery, also spelt Pendlebury; 1575 – November 15, 1641) was the 10th great-grandmother of Cometan, classified as one of Cometan’s distant maternal ancestors in the Prescott family line. Born in Westhoughton, Lancashire, Ann was the daughter of Anne Massey (1550 – 1582) and Rogger Pendlebury. Ann married her husband James Worthington (1575 – 1630) in the year 1600 in Bolton, Lancashire at the age of twenty-five. She is believed to have died in Bolton at the age of sixty-six.
In Cometanic ancestry, Ann is classified as part of the 12th generation retrograde, categorising her as a distant ancestor of Cometan.